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4-ACO-DMT (4-Acetoxy-DMT, Psilacetin) - Image 2

4-ACO-DMT (4-Acetoxy-DMT, Psilacetin)

$120.00 – $1,700.00

4-AcO-DMT (or psilacetin) is a semi-synthetic tryptamine closely related to the psychedelic mushroom molecules psilocin and psilocybin. In fact, 4-AcO-DMT is widely known as “synthetic mushrooms.” Like psilocybin, it appears that the body metabolizes 4-AcO-DMT into psilocin.

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4-acetoxy DMT (hydrochloride) (Item No. 14056) is an analytical reference standard categorized as a tryptamine.1,2 4-acetoxy DMT is a prodrug form of psilocin (Item Nos. 9003135 | 11864 | 36971), a psychedelic hallucinogen derived from various mushrooms. 4-acetoxy DMT induces the head-twitch response (HTR) in mice, indicating hallucinogenic potential.2 This product is intended for research and forensic applications.

WARNING This product is not for human or veterinary use.

Technical Information
Formal Name
3-[2-(dimethylamino)ethyl]-1H-indol-4-ol-4-acetate, monohydrochloride
CAS Number
2748484-99-1
Molecular Formula
C14H18N2O2 • HCl
Formula Weight
282.8
Purity
≥90%
Formulation(Request formulation change)
A solution in acetonitrile
Solubility(Learn about Variance in Solubility)
  • DMF: 30 mg/ml
  • DMSO: 10 mg/ml
  • Ethanol: 20 mg/ml
  • PBS (pH 7.2): 10 mg/ml
λmax
219, 277 nm
SMILES
CN(C)CCC1=CNC2=CC=CC(OC(C)=O)=C21.Cl
InChi Code
InChI=1S/C14H18N2O2.ClH/c1-10(17)18-13-6-4-5-12-14(13)11(9-15-12)7-8-16(2)3;/h4-6,9,15H,7-8H2,1-3H3;1H
InChi Key
OEPCTLAWMZJUIX-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 2 years

Product Description References

1. Nichols, D.E., and Frescas, S. Improvements to the synthesis of psilocybin and a facile method for preparing the O-acetyl prodrug of psilocin. Synthesis 6, 935-938 (1999).

2. Klein, A.K., Chatha, M., Laskowski, L.J., et al. Investigation of the structure−activity relationships of psilocybin analogues. ACS Pharmacol. Transl. Sci. 4(2), 533-542 (2020).

Product Citations

Kozell, L.B., Eshleman, A.J., Swanson, T.L., et al. Pharmacologic activity of substituted tryptamines at 5-HT2AR, 5-HT2CR, 5-HT1AR, and SERT. J. Pharmacol. Exp. Ther. JPET-AR-2022-001454 (2023).

Gatch, M.B., Hoch, A., and Carbonaro, T.M. Discriminative stimulus effects of substituted tryptamines in rats. ACS Pharmacol. Transl. Sci. 4(2), 467-471 (2020).

Quantity

250g, 500g, 1000g, 25g, 100g, 10g

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